These threaded inserts (often called a nutsert or rivet nut) will only be required if your vehicle was NOT equipped with them from the factory. This can often be the case with passenger vans.
Most cargo vans have these pre-installed at the factory. Some passenger vans may also have these but please check your vehicle carefully before ordering. If your vehicle does not have these pre-installed, order two for each grab handle kit meaning a total of four if you are doing two.